Endocrine Abstracts

Background: Whether combination therapy of levothyroxine and liothyronine increases the risk of atrial fibrillation remains a topic of debate.Objectives: The objective of this study was to investigate the risk of atrial fibrillation in individuals with hypothyroidism treated with a combination of levothyroxine and liothyronine.Methods: We conducted a retrospective cohort study using individual-level linkage of Danish nationwide reg...

Introduction: Hypothyroidism has been associated with oxidative stress. Urinary excretion of 8-oxo-7,8-dihydroguanosine (8-oxoGuo) and 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodG), respectively, represent whole-body RNA and DNA oxidation. While these biomarkers have been associated with increased morbidity and mortality in various diseases, they have been only sparsely explored in patients with thyroid disorders.Method: In 45 women with newly diagn...